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Assigning and visualizing germline genes in antibody repertoires
2015
Philosophical Transactions of the Royal Society of London. Biological Sciences
One contribution of 13 to a theme issue 'The dynamics of antibody repertoires'. Identifying the germline genes involved in immunoglobulin rearrangements is an essential first step in the analysis of antibody repertoires. Based on our prior work in analysing diverse recombinant viruses, we present IgSCUEAL (Immunoglobulin Subtype Classification Using Evolutionary ALgorithms), a phylogenetic approach to assign V and J regions of immunoglobulin sequences to their corresponding germline alleles,
doi:10.1098/rstb.2014.0240
pmid:26194754
pmcid:PMC4528417
fatcat:d7ybn2675vfmdc3sh6mp7xsbze