Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues

A. L. Gerbes
1994 Journal of Clinical Endocrinology and Metabolism  
We have compared the expression of atria1 natriuretic peptide (ANP) and brain natriuretic peptide (BNP) genes in various human tissues using a quantitative polymerase chain reaction technique. Tissues of three human subjects, obtained at autopsy, were analyzed. BNP transcripts could be detected in the central nervous system, lung, thyroid, adrenal, kidney, spleen, small intestine, ovary, uterus, and striated muscle. ANP transcripts could also be demonstrated in various human extracardiac
more » ... including several endocrine organs. In all periph-
doi:10.1210/jc.78.6.1307 pmid:8200930 fatcat:telq4wu3indjthdzcwmt5zhnse