Reductive alkylation of active methylene compounds with carbonyl derivatives, calcium hydride and a heterogeneous catalyst

Carole Guyon, Marie-Christine Duclos, Marc Sutter, Estelle Métay, Marc Lemaire
2015 Organic and biomolecular chemistry  
A one-pot two-step reaction (Knoevenagel condensation – reduction of the double bond) has been developed using calcium hydride as a reductant in the presence of a supported noble metal catalyst.
doi:10.1039/c5ob00849b pmid:26053131 fatcat:mqck5hoo5jbqdhqnqrv67uj3jq