Photo Vignette Infantile myofibroma: a firm, round plaque in an infant

Shinya Amano, Mark Halsey, Mariko Yasuda, Patrick O', Donnell Do, Courtney Csikesz, Courtney Csikesz
2016 unpublished
Infantile myofibroma is a rare fibromatous tumor that is variable in presentation and is frequently mistaken for hemangioma or rhabdomyosarcoma. We describe a 14-month-old boy who presented with multiple, enlarging, firm lesions on the shoulder. Biopsy revealed a proliferation of small spindle cells with myxoid and hyalinized stroma infiltrating into the superficial adipose tissue. We provide a brief review of the clinical presentation, histopathologic features, management, and recent advances
more » ... nd recent advances in our understanding of this rare condition. Case synopsis A 14-month-old boy presented with a 3-month history of a "bump" on the right posterior shoulder. The lesion had not changed in size since it was first noticed, but a new, smaller lesion had appeared next to the first within 3 days of presentation. There was no bleeding, pruritus, or pain at the site. Birth history and past medical history were unremarkable except for mild seborrheic dermatitis of the scalp. Physical exam revealed a skin-colored to pink, 11x8 mm, well-demarcated, round, firm nodule with telangiectasia and a central depression with a fine scale in the center. Additionally, a similar 4 mm papule lay superior to the larger lesion (Figure 1, A-C). A punch biopsy was obtained.
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