worse prognosis hazard ratio=3.6 (95% CI=1. 24-10.44, p = 0.00184). Although the NT-pro BNP correlated with LVEF its association with outcome was independent of this. Conclusions In a prospective mixed cohort of patients with AS undergoing investigations for consideration of aortic valve intervention, even a mild elevation in NT-pro BNP is associated with worse short term outcome. This can be taken into consideration regarding timing of intervention especially in the asymptomatic population.