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A non-linear programming model was developed to maximize the economic profit from an anaerobic codigester. The model consists of a combination of technical and economic equations, linked through the biogas production variable. Five scenarios were simulated. These differed with regard to substrate inlet mass flow rate, organic loading rate and hydraulic retention time. The impact on biogas production was investigated and an economic analysis was undertaken based on the concepts of profitabilitydoi:10.1016/j.renene.2016.01.081 fatcat:2vkfpam2hrcjrm5aw2s6ij6poq