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Experimental Protocol for MRI Mapping of the Blood Oxygenation-Sensitive Parameters T2* and T2 in the Kidney
2021
Msphere
Renal hypoxia is generally accepted as a key pathophysiologic event in acute kidney injury of various origins, and has also been suggested to play a role in the development of chronic kidney disease. Here we describe a step-by-step experimental protocol for indirect monitoring of renal blood oxygenation in rodents via the deoxyhemoglobin sensitive MR parameters T2* and T2-a contrast mechanism known as the blood oxygenation level dependent (BOLD) effect. Since an absolute quantification of renal
doi:10.1007/978-1-0716-0978-1_23
pmid:33476013
pmcid:PMC9703278
fatcat:lrllwrj2fbhxzmbe6vax5rt37q