Antagonistic Activation Patterns Underlie Multi-functionality of the Right Temporo-Parietal Junction

Danilo Bzdok, Robert Langner, Simon Eickhoff, Angela R. Laird, Peter T. Fox
2013 2013 International Workshop on Pattern Recognition in Neuroimaging  
The right temporo-parietal junction (RTPJ) is consistently implicated in two cognitive domains -attention and social cognitions. We conducted multi-modal connectivitybased parcellation to investigate potentially separate functional modules within RTPJ implementing this cognitive dualism. Both task-constrained meta-analytic coactivation mapping and task-free resting-state connectivity analysis independently identified two distinct clusters within RTPJ, subsequently characterized by network
more » ... g and functional forward/reverse inference. The anterior cluster increased activity concomitantly with a midcingulate-motor-insular network, functionally associated with attention, and decreased activity with a parietal network, functionally associated with social cognition and introspection. The posterior cluster showed the exactly opposite association pattern. Our data thus suggest that RTPJ links two antagonistic brain networks processing external versus internal information. anti-correlation, connectivity-based parcellation, functional decoding, temporo-parietal junction I. 3rd International Workshop on Pattern Recognition in Neuroimaging 978-0-7695-5061-9/13 $26.00
doi:10.1109/prni.2013.25 dblp:conf/prni/BzdokLELF13 fatcat:yfxeuspn4fhn3ffnlvim3lbrni