Correlation of Sonographic Grading of Renal Cortical Echogenicity with Serum Creatinine in Patients with Chronic Kidney Disease

Chidananda Murthy. M, Assistant Professor, Department of Radio-Diagnosis, A.J. Institute of Medical Sciences and Research Centre, Kuntikana, Mangalore -575004., Bharath Kumar Shettty K, Ganesh K, Francis N. P. Monteiro, Assistant Professor, Department of Radio-Diagnosis, A.J. Institute of Medical Sciences and Research Centre, Kuntikana, Mangalore -575004., Professor & HOD, Department of Radio-Diagnosis, A.J. Institute of Medical Sciences and Research Centre, Kuntikana, Mangalore -575004., Professor, Department of Forensic Medicine & Toxicology, A.J. Institute of Medical Sciences and Research Centre, NH 17, Kuntikana, Mangalore -575004.
2019 Asian Journal of Medical Radiological Research  
Ultrasound Imaging can be used as a painless, non-invasive modality for the grading of renal echogenicity in chronic kidney disease (CKD). Aims: To determine the association of renal echogenicity in persons with CKD using ultrasound and serum creatinine Settings and Design: Retrospective observational study design at a single center. Subjects and Methods: The study included 112 subjects aged 18 to 90 years with CKD, with grades of renal echogenicity and renal length estimates based on
more » ... based on ultrasound findings and biochemical test results of serum creatinine profile. Renal size was categorized as optimal or small or enlarged and renal echogenicity graded from 1 to 4. Statistical Analysis used: A one way Analysis of Variation test (ANOVA) was used to compare the renal echogenicity and renal length with serum creatinine. Pairwise correlations were estimated and a p value of <0.05 was considered as statistically significant. Results: The study included 112 subjects with a mean age (SD) of 54.37 (17.29 years) and 81 (72.32%) subjects were males. The majority of patients (n=51, 45.54%) in the study were aged 60 years or older. Sixty eight subjects (60.71%, 95% CI: 51.45, 69.43) subjects had optimal sized kidneys and 8 (7.14%, 95% CI: 3.66, 13.46) subjects had significant discrepancy in renal size. The majority of subjects (n=43, 38.74%, 95%CI: 29.73, 47.64) in the study had Grade 1 renal echogenicity. Serum creatinine values increased significantly with increasing grades of renal echogenicity (F=9.58, p<0.001, one way ANOVA test). The grade of echogenicity and serum creatinine levels showed a statistically significant correlation (p<0.001) on pairwise correlation test. The mean longitudinal renal length was significantly associated (F=14.07, p<0.001) with renal echogenicity. Conclusion: Serum Creatinine levels and renal echogenicity were significantly associated in this study. Ultrasound imaging studies can be a painless non-invasive alternate in the evaluation of CKD.
doi:10.21276/ajmrr.2018.6.2.8 fatcat:oyrnb77w3jdlhmkekrzxfuribu