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Effect of Weight Loss on the Pulsatile Insulin Secretion
2000
Journal of Clinical Endocrinology and Metabolism
The aim of the study was to assess whether pulsatile insulin secretion is variable in the same individual and is related to changes in insulin sensitivity. Insulin sensitivity and pulsatility were measured before and after weight reduction in nine obese subjects. A pulsatility analysis was done using the PulsDetekt program. Blood was sampled every 2 min over a period of 90 min. The secretion randomness was quantified using approximate entropy (ApEn), and ApEn normalized by SD of the insulin
doi:10.1210/jcem.85.10.6919
pmid:11061521
fatcat:zttjegrfzvb35bgmytknuduvii