Brain volume abnormalities and neurocognitive deficits in diabetes mellitus: Points of pathophysiological commonality with mood disorders?

Roger S. McIntyre, Heather A. Kenna, Ha T. Nguyen, Candy W. Y. Law, Farah Sultan, Hanna O. Woldeyohannes, Mohammad T. Alsuwaidan, Joanna K. Soczynska, Amanda K. Adams, Jenny S. H. Cheng, Maria Lourenco, Sidney H. Kennedy (+1 others)
2010 Advances in Therapy  
It is hypothesized that diabetes mellitus (DM) and mood disorders share points of pathophysiological commonality in the central nervous system. Methods: A PubMed search of all English-language articles published between 1966 and March 2009 was performed with the following search terms: depression, mood disorders, hippocampus, amygdala, central nervous system, brain, neuroimaging, volumetric, morphometric, and neurocognitive deficits, cross-referenced with DM. Articles selected for review were
more » ... sed on adequacy of sample size, the use of standardized 0011-z 2 63 64 Adv Ther (2010) 27(2):63-80.
doi:10.1007/s12325-010-0011-z pmid:20390390 fatcat:y57nbrwz7fbivfhci2lwknv7gu