Detecting active ingredients of insect repellents and sunscreens topically in skin by Raman spectroscopy

Michele Marin da Costa, Leandro Procópio Alves, Rodrigo Alexis Lazo Osório, Marcos Tadeu Tavares Pacheco, Landulfo Silveira
2018 Journal of Biomedical Optics  
Detecting active ingredients of insect repellents and sunscreens topically in skin by Raman spectroscopy," J. Abstract. We present the use of Raman spectroscopy for determination of functional characteristics of insect repellents and sunscreens by identifying the active ingredients of these products applied topically to the skin. Commercial formulations of insect repellents and sunscreens (SPF 15 and 30) were obtained, and Raman spectra were obtained from the formulations and from volunteers'
more » ... from volunteers' skins with topical applications of such products compared to controls. The results indicated that, for insect repellents, the peaks at 527 and 1003 cm −1 were markers of the presence of the active ingredient diethyl toluamide in the skin, while for sunscreens, the peaks at 1177, 1288, and 1611 cm −1 , associated to octinoxate, benzophenone-3, and avobenzone, were markers of the presence of solar filters in the skin. The results suggested reliability in the use of Raman spectroscopy to identify the active ingredients of insect repellents and sunscreens topically applied on the skin; the applied methodology can be used to determine the functional characteristics of topical products with similar characteristics.
doi:10.1117/1.jbo.23.10.107003 fatcat:4euaviqqgrcxjlv2qh45wfn2xe