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The effect of holothurin on leucocyte migration
Zoologica; scientific contributions of the New York Zoological Society
Crude Holothurin, purified Holothurin A, and desulfated Holothurin A, water soluble steroid saponins from the Cuvierian organs of the Bahamian sea cucumber Actinopyga agassizi Selenka, cause a stimulation of leucocyte migration from buffy layer in capillary tubes in relatively low concentrations and an inhibition of the movements at higher concentrations. The inhibitory properties are compared with similar effects by Ouabain, a non-hemolytic saponin, and by liberated hemoglobin. The Holothurinsdoi:10.5962/p.206666 fatcat:b4dodfu3ljhb3h36pkefloddyu