Synthesis of 3-trifluoromethylpyrazoles via trifluoromethylation/cyclization of α,β-alkynic hydrazones using a hypervalent iodine reagent

Guojing Ji, Xi Wang, Songnan Zhang, Yan Xu, Yuxuan Ye, Ming Li, Yan Zhang, Jianbo Wang
2014 Chemical Communications  
A mild and efficient method for the synthesis of 3-trifluoromethylpyrazoles has been established via trifluoromethylation/cyclization of α,β-alkynic hydrazones using a hypervalent iodine reagent.
doi:10.1039/c4cc01280a pmid:24643782 fatcat:55anft4wcnhl7g24jmyejrsjsi