Novel flexible light diffuser and irradiation properties for photodynamic therapy

Baerbel Selm, Markus Rothmaier, Martin Camenzind, Tania Khan, Heinrich Walt
2007 Journal of Biomedical Optics  
Many current light diffusers for photodynamic therapy are inflexible, and the applied light dose is difficult to adjust during treatment, especially on complex body surfaces. A thin and flexible luminous textile is developed using plastic optical fibers as a light distributor. The textile diffuser is evaluated for flexibility, irradiance, brightness distribution, and temperature rise with a 652-nm laser set to 100 mW. The bending force of the textile diffuser resembles a defined optical film.
more » ... the textile surface, an average output power of 3.6± 0.6 mW/ cm 2 is measured, corresponding to a transmission rate of 40± 3.8% on an area of 11 cm 2 . Aluminum backing enhances the irradiance to the face ͑treatment side͒. The measured brightness distribution seems to lie within a range similar to other photodynamic therapy ͑PDT͒ devices. A power setting of 100 mW increases the temperature of the textile diffuser surface of up to 27°C, and 1Wraises the temperature above 40°C. Results confirm that the flexible textile diffuser supplies suitable radiation for low fluence rate photodynamic therapy on an area of several cm 2 .
doi:10.1117/1.2749737 pmid:17614732 fatcat:fmvwurhhmfblhfvqwbtaudli4q