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Genome-Wide Profiling of a Prognostic RNA-Binding Protein Signature in Esophageal Cancer
Background the roles of RNA-binding proteins (RBPs) in esophageal cancer (EC) need elucidation. Materials and methods The gene expression profiles and clinical data of patients with EC were downloaded from the Xena database. Candidate genes were obtained by taking the union of RBP genes, KEGG pathway-related genes and differentially expressed RBP genes from cluster analysis. Hub genes were extracted by PPI network construction. Result We built a Cox proportional hazards regression model with 7doi:10.21203/rs.3.rs-1439005/v1 fatcat:cbcvp7i5ijcunj53kcfkrjan2a