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Potential Drugs Targeting Nsp16 Protein May Corroborates a Promising Approach to Combat SARSCoV-2 Virus
[post]
2020
unpublished
<p>The recent ongoing pandemic caused by SARS-CoV-2 continues to impose devastating impacts and is accountable for the loss of more than 250,000 human lives within a short span of four months. This urges immediate therapeutic measures to control the impact of this disease. One of the most conserved and potentially druggable sites is the Nsp16 active site that performs the 2'-O-methyltransferase activity and puts a 5' cap on the viral RNA molecules. This allows them to mimic endogenous
doi:10.26434/chemrxiv.12279671.v1
fatcat:caqh6flg7zbupdjhtplg2y3ici