The leiomyoma is a benign smooth muscle tumor and may occur throughout the entire digestive tract, more frequently in the stomach, and small intestine, but is rarely seen in large bowel. Furthermore, a colonic giant pedunculated leiomyoma is very rare. The traditional management option for a colonic leiomyoma is surgical resection. However, the endoloop-assisted polypectomy could be the treatment of choice even for very large lesions. Abstract This is an open access article distributed under

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