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The Importance of Standardization on Analyzing Circulating RNA
2016
Molecular Diagnosis & Therapy
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Circulating RNAs, especially microRNAs (miRNAs) have recently emerged as non-invasive disease biomarkers. Despite enthusiasm and numerous reports on disease associated circulating miRNAs, currently there is no circulating miRNA-based diagnostic in use. In addition, there are many contradictory reports on the concentration changes of specific miRNA in circulation. Here we review the impact of various technical and non-technical factors related to circulating miRNA measurement and elucidate the
doi:10.1007/s40291-016-0251-y
pmid:28039578
pmcid:PMC5426982
fatcat:56s42d6l6narze4mp6lhnxubda