This paper explores the relationship between CSCW studies of scientific collaboration and the larger worlds of science practice and policy they are embedded in. We argue that CSCW has much to learn from debates in science policy, including questions around the changing nature of science and science-society relations that are partly but obliquely referenced in technology-or data-centered accounts of scientific change. At the same time, science policy has much to learn from CSCW -about design,

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... rastructure, and the organizational complexities of distributed collaborative practice. We conclude with recommendations for a better integration of the CSCW and science policy literatures around collaboration and new infrastructure development in the sciences, and speculation around what a post-normal cyberinfrastructure -and post-normal CSCWmight look like.