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Determination of cefotaxime, cefoperazone, ceftazidime and cefadroxil using surface plasmon resonance band of silver nanoparticles
Brazilian Journal of Pharmaceutical Sciences
The aim of this work is to evaluate simple, sensitive, effective and validated procedures for the determination of cefotaxime, cefoperazone, ceftazidime and cefadroxil. In this study, the methods based on the ability of the cited drugs to reduce Ag + ions to silver nanoparticles (Ag-NPs) in the presence of Polyvinyl Pyrrolidone (PVP) as a stabilizing agent producing very intense surface plasmon resonance peak of Ag-NPs (λ max. = 410-430 nm). The plasmon absorbance of the Ag-NPs allows thedoi:10.1590/s2175-97902018000317565 fatcat:4irxviuganclrezo46yg5i2yne