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Acne is a manifestation of hormonal overstimulation of the pilosebaceous units of genetically susceptible individuals and may manifest in the form of comedonic, papulopustular or nodular lesions. It can present as an isolated disease or in the context of clinical syndromes; among these congenital adrenal hyperplasia (CAH),a group of autosomal recessive disorders resulting from deficiency of one of the five enzymes required for synthesis of cortisol in the adrenal cortex. The most common form ofdoi:10.1017/s0956792509007876 fatcat:hctpikorljdczcipgkfiujzsyy