Chemoprevention of electrophilic damage by mercaptopurine analogs [article]

Michael C. MacLeod, Austin, The University Of Texas At, Austin, The University Of Texas At
2019
Analogs of 6-mercaptopurine have been found to enhance the detoxification of various electrophilic toxicants in vivo, while having minimal cytotoxicity themselves. This property allows such compounds to act as scavengers for electrophilic toxicants, thereby preventing the cellular damage caused by such toxic agents.
doi:10.26153/tsw/4462 fatcat:74nsntvbxnbmjdjlqohrfbgpna