Synthesis, characterization, molecular docking and evaluation of antimicrobial, antiproliferative, and anti-inflammatory properties of new 4-biphenyl substituted thiazolyl-pyridin-2-amine derivatives

Bettadapura Gundappa, Krishna, Balladka Kunhana Sarojini, Umesha Kundapur, Chenna Darshanraj
2014 Scholars Research Library Der Pharma Chemica   unpublished
Gentles et al reported SAR study on a series of apamin-displacing 2-aminothiazole K Ca 2 channel blockers, Potent inhibitors such as N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine, and for select members of the series, the relationship between the observed activity in a thallium flux, a binding and a whole-cell electrophysiology assay was also presented [7]. Bettadapura Gundappa Krishna et al Der Pharma Chemica, 2014, 6 (4):233-243 _____________________________________________________________________________