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Studies of the cardiac-like action potential in crayfish giant axons induced by platinized tungsten metal electrodes
Journal of Experimental Biology
A lightly platinized tungsten (Pt-W) wire electrode, axially inserted into a crayfish giant axon, causes the development of cardiac-like action potentials with durations of up to 4 s. The plateau in membrane potential typically occurs within 10 min of the start of action potential elongation. The effect occurs without passing current through the Pt-W electrode and is temporally related to a dramatic decrease in intracellular pH (pHi). Such an effect cannot be induced by a decrease in pHipmid:3559460 fatcat:6kaed2e74ve5fdcrk4xvg7sqfi