Extracorporeal shock wave lithotripsy for gallbladder stones: an experimental and clinical study

K S Kim, S M Park, J H Lee, Y G Kim, K S Song, K S Lee, J B Lee, S J Kim, S T Chang
1988 Journal of the Korean Radiological Society  
Although m any alternative treatment technics have been proposed recently for gallstone to substitute cholecystectomy, the extracorporeal shock wave lithotripsy (ESW니 for gallbladder stones has rare ly been tried We have ca rried o ut a series of experiments to evaluate how effective the ESWL for ga ll bladder ston es is and how safe this proced ure is At first, in vitro shock wave application was ca rried o ut to 10 gallbladd er stones wh ich were obtain ed Irom human gallbladder. Secondly, ga
more » ... llblad der stones were implanted to canin e gallbladder and treated with shock wave. Lastly, a total 0141 vo lunteers w ith conlirmed gallblad der ston es were treated with shock wave and co mbined o ral adm ini stration 01 urso deoxycho li c acid In the in vitro ex periment, all 01 the 10 gal lsto nes we re Iragmen ted w ith variabl e liring ra tes and duration In animal experim ent, the implanted stones we re successlully Iragmented and the organs included in the pathway 。 1 shock wave were proved to be intact histologically. In human study, comp lete disappea rance 01 gallstones was noted in 78.6% 01 patients w ith single radio lu cent gallbladder stones, smaller th an 2.5cm in the longest diameter. Two patients und erwent cholecystectomy alter ESWL due to sudden colic attack. One patient had experi enced an ep isod e 01 mild transient obstructi ve jaundice It may be concluded that the ESWL lor gal lbladder stones is an effective and sale method 01 treatment 01 gallbladder stones in the selected cases, lor examp le, small rad iolucent stones, and the lurthe r study is needed to establish improved technology 01 th e ESWL lor gallb ladder stones • 중앙 대학교 의파 대 학 내 과학교실
doi:10.3348/jkrs.1988.24.4.630 fatcat:afjrpdq55fa5pmngqbndxt6zwa