Kinetic Resolution of Racemic Allylic Alcohols via Iridium-Catalyzed Asymmetric Hydrogenation: Scope, Synthetic Applications and Insight into the Origin of Selectivity

Haibo Wu, Cristiana Margarita, Jira Jongcharoenkamol, Mark D Nolan, Thishana Singh, Pher Andersson
2021 Chemical Science  
Asymmetric hydrogenation is one of the most commonly used tools in organic synthesis, whereas, kinetic resolution via asymmetric hydrogenation was less developed. Herein, we describe the first iridium catalyzed kinetic...
doi:10.1039/d0sc05276k fatcat:dijt6z7ggbb23bcdtwtowirxxm