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Anti-hepatitis B core antibody (Anti-HBc) alone is defined as the presence of anti-HBc in the absence of HBsAg and anti-HBs. The significance of this serological pattern as a predicting factor for occult hepatitis B virus (HBV) infection remains largely unknown. This study aimed to assess the significance of anti-HBc alone in predicting occult HBV infection in high-risk and low-risk individuals. Methodology: A total of 926 individuals were enrolled in this study, including 289 hemodialysis (HD)doi:10.3855/jidc.728 fatcat:nf4bhzgyg5c5djewmhml63ofve