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The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles
Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, continually exposed to mechanical signals and biochemical components generated in the blood compartment. They are involved in all the physiological functions and the pathological changes taking place in the vascular wall. Owing to their contractile tonus, VSMCs of resistance vessels participate in the regulation of blood pressure and also in hypertension. VSMCs of conduit arteries respond to hypertension-induceddoi:10.1093/cvr/cvs135 pmid:22467316 fatcat:h2epel7mprbjrijx3cyfmcdp54