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We have built a thermocycler based on the principles of induction heating for polymerase chain reaction (PCR) of target sequences in DNA samples of interest. The cycler has an average heating rate of ϳ0.8°C/s and a cooling rate of ϳ0.5°C/s, and typically takes ϳ4 h to complete a 40-cycle PCR protocol. It is power-efficient (ϳ6 W per reaction tube), micro-processor controlled, and can be adapted for battery operation. Using this instrument, we have successfully amplified a 350 bp segment from adoi:10.1063/1.1781368 fatcat:x43ypg2bh5ehffvmtkhzamm4aq