A Patient with Wegener's Granulomatosis with Initial Clinical Presentations of Henoch-Schoenlein Purpura

Masayuki MIYATA, Kaori KANNO, Tomoe NISHIMAKI, Fumitaka SAKUMA, Keiji IWATSUKI, Reiji KASUKAWA
2001 Internal medicine (Tokyo. 1992)  
The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Schonlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Schonlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation.
more » ... s inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.
doi:10.2169/internalmedicine.40.1050 fatcat:htzvfeid3bdh5iqgjg54jg37p4