Intravitreous Bevacizumab Injection

Rafael T. Cortez
2010 Archives of Ophthalmology  
Objectives: To determine the effects of intraocular pressure (IOP) and needle diameter on the amount of reflux after intravitreous bevacizumab injection. Methods: Prospective randomized interventional study. Twelve New Zealand white rabbits weighing approximately 2.5 to 3.5 kg each were randomized 1:1 to group 1 or group 2. Bevacizumab stained with trypan blue was used for intravitreous injection. To lower the IOP, eyes in group 2 underwent anterior chamber paracentesis before intravitreous
more » ... ction. Two eyes in each group were injected using 27-, 30-, or 32-gauge needles. If a subconjunctival bleb formed after intravitreous injection, its diameter was measured using a caliper.
doi:10.1001/archophthalmol.2010.139 pmid:20625050 fatcat:ghtca4rlm5bizazfo3zxtr3olu