A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
Focal Adhesion Kinase Overexpression Induces Enhanced Pathological Retinal Angiogenesis
Investigative Ophthalmology and Visual Science
PURPOSE. Focal adhesion kinase (FAK) is involved in processes integral to angiogenesis, such as cell growth, survival, and migration. FAK is activated by angiogenic growth factors, such as insulin-like growth factor (IGF)-I, vascular endothelial growth factor (VEGF), and basic fibroblast growth factor (bFGF). The study was conducted to determine whether overexpression of FAK or FAK-related nonkinase (FRNK), an inhibitor of FAK, could influence human retinal endothelial cell (HREC) migration anddoi:10.1167/iovs.03-1201 pmid:15557455 fatcat:ey76iwxmdbdgdls7xjluhfcdpe