Posterior Capsular Opacification is due to growth and abnormal proliferation of lens epithelial cells over the posterior capsule which migrate towards the visual axis causes obscuration of vision. Aim: To compare the incidence of Posterior Capsular Opacification following implantation of PMMA Intra ocular lenses with that of Hydrophobic Acrylic Intra ocular lenses after cataract surgery over senile cataract. Materials and Methods: A Total of 200 patients operated by a single surgeon is made

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... 2 groups. Group A with 109 patients with senile cataract operated by Phacoemulsification with PMMA IOL implantation and Group B with 91 patients with senile cataract operated by phaco emulsification with Hydrophobic Acrylic IOL implantation is studied for a period of 4 years from 2014 to 2018 for the formation of PCO. PCO was analysed and graded under Slit Lamp examination. Data were compared between two groups. Results: A total of 200 eyes underwent Phacoemulsification with IOL implantation. There were 109 patients in group A on whom PMMA lens were implanted. In Group B there were 91 patients on whom hydrophobic Acrylic IOLs been implanted. In group A 28(25.6%) patients developed PCO and in Group B, 11(12.08%) patients developed PCO in the follow up study. Conclusion: Hydrophobic Acryllic IOLs have lesser rate of posterior capsular opacification rate compared to PMMA IOLs.