P45 IL-2 THERAPY REDUCES RENAL INFLAMMATION AND CELLULAR ACTIVITY OF INTRARENAL CD4+ CONVENTIONAL T CELLS IN LUPUS PRONE MICE WITH ACTIVE LUPUS NEPHRITIS

A. Rose, C. von Spee-Mayer, L. Kloke, K. Wu, P. Enghard, A. Kühl, J.Y. Humrich, G. Riemekasten
2016 Kidney International Reports  
with resolution of AKI, we observed a persistence of macrophages and T cells (>10days). Conclusions: The amount of renal epithelial cells in the urine seems to directly reflect tissue damage in AKI. Immune cells can be monitored in the urine of patients with AKI and persisted longer than the renal injury itself. This suggests that immune cells participate in mediating damage and tissue repair in human AKI.
doi:10.1016/j.ekir.2016.09.051 fatcat:csdmhz4pdzdazoqtvto667r7ga