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IN VIVO AND IN VITRO PROLACTIN SECRETION BY TRANSPLANTED RAT "MAMMOTROPIC" PITUITARY TUMORS
1964
Cancer Research
The functional, transplanted, autonomous rat pituitary â€oemammotropic―tumor (Furth, MtT.F4) was compared with normal rat pituitary for capacity to elaborate prolactin in vivo and in vitro. The prolactin content of transplanted anterior pitui tary (AP) and MtT.F4, as measured by the intradermal pigeon crop technic, was 1.6 and 4.8 per cent, respectively, of that present in the AP in situ. Considerable amounts of prolactin were detected in the blood plasma of rats bearing an MtT.F4, the levels
pmid:14230918
fatcat:t2mh6wa5mbgfbijp5crkzz432y