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Decision letter: Quantifying the relationship between SARS-CoV-2 viral load and infectiousness
The relationship between SARS-CoV-2 viral load and infectiousness is poorly known. Using data from a cohort of cases and high-risk contacts, we reconstructed viral load at the time of contact and inferred the probability of infection. The effect of viral load was larger in household contacts than in non-household contacts, with a transmission probability as large as 48% when the viral load was greater than 10 10 copies per mL. The transmission probability peaked at symptom onset, with a meandoi:10.7554/elife.69302.sa1 fatcat:rle2schl4vadpcg723ck53mqum