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PPARG Post-translational Modifications Regulate Bone Formation and Bone Resorption
2016
EBioMedicine
PPARG Post-translational modifications regulate bone formation and bone resorption EBioMedicine, 2016; 10:174-184 a b s t r a c t The peroxisome proliferator-activated receptor gamma (PPARγ) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. However, clinical use of TZDs has been limited by side effects including a higher risk of fractures and bone
doi:10.1016/j.ebiom.2016.06.040
pmid:27422345
pmcid:PMC5006645
fatcat:vh5huwusg5d65pse2osknpbwzq