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Integrating long-range connectivity information into de Bruijn graphs
2018
Bioinformatics
Motivation: The de Bruijn graph is a simple and efficient data structure that is used in many areas of sequence analysis including genome assembly, read error correction and variant calling. The data structure has a single parameter k, is straightforward to implement and is tractable for large genomes with high sequencing depth. It also enables representation of multiple samples simultaneously to facilitate comparison. However, unlike the string graph, a de Bruijn graph does not retain long
doi:10.1093/bioinformatics/bty157
pmid:29554215
pmcid:PMC6061703
fatcat:7ksbpf6i7nfofajzazgezy5ohe