This review demonstrates the most important sensitive diagnostic methods, and appropriate management of UGIB. A literature search and Narrative review was carried out on Databases including MEDLINE (PubMed), EMBASE, to discuss the upper gastrointestinal bleeding. Studies were selected depending in with study can provide comprehensive review of conserving topic. UGIB is a medical urgent condition with high mortality which can be resolved by correct evaluation and management. A validated scoring

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... ystem can assist the doctors to decide about the level of care, timing of endoscopy, and when to discharge the patient. The threat of apoplexy should be weighed against the danger of bleeding prior to holding the anticoagulation and antiplatelet therapy in UGIB. Endoscopy needs to be carried out after hemodynamically stabilizing the patient. Prompt assessment and resuscitation are essential, as are threat stratification of the severity of bleeding, early participation of the multidisciplinary group and prompt access to endoscopy, ideally within 24 h. The majority of GI bleeding is due to peptic ulcers for which Helicobacter pylori and non-steroidal anti-inflammatory agents are the main causative aspects.