Risk Factors Determining the Outcome of 2-12 Months Age Group Infants Hospitalized With Severe Pneumonia
Pneumonia is one of the leading causes of morbidity and mortality in under fives throughout the world, particularly in developing countries. A case control study was carried out in Bangabandhu Memorial Hospital, University of Science and Technology during the period of January to July 2006. 192 hospitalized infants of 2-12 months age group with World Health Organization(WHO) defined severe pneumonia with radiological confirmation were enrolled in the study, while controls were normal infant of
... e normal infant of same age group attending EPI center for vaccination. The children were managed using a standard protocol, factors were examined by univariate logistic regression analyasis. The factors whose odds ratio were significantly below 25% and considered as medically important were included in multivariate logistic regression analysis. Out of 192 children, 136(70.8%) were male, 56(29.2%) were female, 2-6 months old infants were 120(62.5%), >6 -12 months infants were 72(37.5%), malnutrition were present in 155( 80.72%), 145(75.5%) lived in slum area, 66(33.7%) were treated by quack, 63% were completely immunized and 3(10.5%) died. On multivariate analysis the following risk factors were found significant i.e. malnutrition, indoor smoke resulting from burning wood and manure used as fuel, non immunization, poor economy , poor housing. Significant risk factors for mortality in severe pneumonia are associated with 3rd degree malnutrition and congenital abnormality of heart with Downs syndrome. Malnutrition, indoor smoke, non-immunization, poor economy, poor housing, and smoking in bed room are important risk factors associated significantly with severe pneumonia and fatal outcome was associated with 3rd degree malnutrition.