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Conventional brain MRI cannot always distinguish between different white matter lesions. Susceptibility weighted imaging (SWI) can detect a sign called central vein sign which is suggested to discriminate between multiple sclerosis and other white matter lesions thus increasing the accuracy of MRI in MS diagnosis. This study aimed to evaluate the role of MR susceptibility weighted imaging in differentiating MS from CSVD lesions. Results: The central vein sign (CVS) was found to have a premiumdoi:10.1186/s43055-020-00185-3 fatcat:i6sl4ls3obf5tadfi3nlw7n7vu