To Determine the Effects of Copper, Zinc and Magnesium in Patients with Pre-Eclampsia

2017 JLUMHS  
OBJECTIVES: Pre-eclampsia is hypertensive and multi-system related disorder of pregnancy. It has frequently labeled as "disease of theories". 5-10% of pregnancies complicated due to pre-eclampsia and it is most common health problem worldwide. This study intended to estimates the copper, zinc and magnesium levels in patients with pre-eclampsia. METHOD: Total eighty subjects were included in the present study, from which 40 voluntaries were normotensive healthy pregnant women (controls), 40 were
more » ... (controls), 40 were pre-eclamptic patients (cases). The subjects were recruited having symptoms of interest after taking obstetric history, anthropometric and clinical data. After taking informed consent, blood sample collected and stored for biochemical analysis. The serum zinc, copper and magnesium levels were analyzed by Atomic Absorption Spectrophotometer. The study was conducted in biochemistry department during period of eight months from October 2015 to June 2016. RESULTS: Total eighty subjects were included in present study. The trace elements decreased and shows significant difference between control healthy pregnant and pre-eclamptic women (p<0.05). The mean difference of copper (0.15±0.07), zinc (2.94±0.45) and Mg ++ (0.15±0.09) mg/dl for the cases group and for control group copper was (0.20±0.03), zinc (5.11±0.21) and Mg ++ (2.17±0.21) mg/dl respectively. CONCLUSION: Trace elements are essential for the healthy pregnancy, suppressed concentration of serum Zinc, Copper and Magnesium may put forward the possible involvement in the pathology of pre-eclampsia. The aim of this study was to protects the mothers as well as her coming newborn from such life threating disease.
doi:10.22442/jlumhs.171610506 fatcat:lh54eoe7ubajpi42tov6xcrkli