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Ceftriaxone is a third generation cephalosporin with a prolonged half life. It was used in doses of 500 mg intramuscularly in 27 men (group 1) and 23 women (group 2) and 250 mg in 48 men (group 3) and 45 women (group 4) with uncomplicated urogenital gonorrhoea. Similar numbers of patients in each group were treated with 2 MIU intramuscular Bicillin (procaine penicillin 1[5 g plus benzylpenicillin 300 mg (Brocades, Weybridge, Surrey, England). Success of treatment was measured as one or twodoi:10.1136/sti.62.2.78 fatcat:6smhx4tm2rbnnkbxs6a76tr4pa