Osteoporosis is a common health problem not only among women but also among men, thus covering general population, regardless of gender. The article deals with question of etiology, pathogenesis, presence of risk factors (modifiable and non-modifiable), laboratory and instrumental methods of diagnostics of this disease. Special aspects of the development of osteoporosis in men and women were considered in detail, and demonstrated that the level of estradiol in blood serum is associated with the

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... severity of osteoporosis in men. Bone mineral density is directly related to the level of estrogen and not testosterone, both in young men and elderly.