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this manuscript is communicated by the german AIds society (dAIg) (www.daignet.de). It summarizes a series of presentations and discussions during a workshop on immune activation due to HIV infection. the workshop was held on november 22 nd 2008 in Hamburg, germany. It was organized by the IcH Hamburg under the auspices of the german AIds society (dAIg e.V.). Eur J Med Res (2010) 15: 1-12doi:10.1186/2047-783x-15-1-1 fatcat:dq7ajx5o6vcczhguhufqw7c3i4