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Effect of Allium sativum (garlic) methanol extract on viability and apoptosis of human leukemic cell lines
Tropical Journal of Pharmaceutical Research
Purpose: To investigate the effect of Allium sativum (garlic) methanol extract on viability and apoptosis of human leukemic cells. Methods: Cell viability was determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay at concentrations of 3. 125, 6.25, 12.5, 25, 50, 100, 200, 400 and 800 ug/mL of Allium sativum extract following 48-h treatment on U-937, Jurkat Clone E6-1 and K-562 cell lines. The mode of cell death was determined by Annexin V-FITC staining anddoi:10.4314/tjpr.v15i7.18 fatcat:ezfgpxd54nafxobuxnuiuq27ie