Quantitative validation of optical flow based myocardial strain measures using sonomicrometry

Qi Duan, Katherine M. Parker, Auranuch Lorsakul, Elsa D. Angelini, Eiichi Hyodo, Shunichi Homma, Jeffrey W. Holmes, Andrew F. Laine
2009 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro  
Dynamic cardiac metrics, including myocardial strains and displacements, provide a quantitative approach to evaluate cardiac function. However, in current clinical diagnosis, largely 2D strain measures are used despite that cardiac motions are complex 3D volumes over time. Recent advances in 4D ultrasound enable the capability to capture such complex motion in a single image data set. In our previous work, a 4D optical flow based motion tracking algorithm was developed to extract full 4D
more » ... cardiac metrics from such 4D ultrasound data. In order to quantitatively evaluate this tracking method, in-vivo coronary artery occlusion experiments at various locations were performed on three canine hearts. Each dog was screened with 4D ultrasound and sonomicrometry data was acquired during each occlusion study. The 4D ultrasound data from these experiments was then analyzed with the tracking method and estimated principal strain measures were directly compared to those recorded by sonomicrometry. Strong agreement was observed independently for the three canine hearts. This is the first validation study of optical flow based strain estimation for 4D ultrasound with a direct comparison with sonomicrometry using in-vivo data.
doi:10.1109/isbi.2009.5193082 pmid:20694163 pmcid:PMC2916658 dblp:conf/isbi/DuanPLAHHHL09 fatcat:wfelbv4ycrdfljnfcvytrzpbkq