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Ursodeoxycholate-induced choleresis in taurine-deprived and taurine-supplemented rats
1985
The Japanese Journal of Physiology
The effect of i.v. infused ursodeoxycholate (1.2 ,umol/(min 100 g body weight)) was compared in control rats and in taurine supplemented (i.p. administration of a taurine solution) and taurine deprived (oral administration of 13-alanine) rats. In the control rats, the bile water output during the first hr was significantly lower than that of the second hr, while the bile salt output was significantly lower in the second hr. In j3-alanine pretreated rats, the increase in the bile flow in the
doi:10.2170/jjphysiol.35.443
fatcat:y3pmekagdndqzg53c4whhp6zxu