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Lymphocytic Profile and Ebv Serology in Sjögren's Syndrome: Evidences for a Virally Triggered Autoimmune Epithelitis?
[post]
2020
unpublished
Sjögren's Syndrome (SjS) is characterized by lymphocytic infiltration of exocrine glands, i.e. autoimmune epithelitis. Lymphocytes are central in SjS pathogenesis, with B-cell hyperactivity mediated by T-cells. B-cells are main targets of Epstein-Barr virus (EBV) infection, a frequently-suggested trigger for SjS.We aimed to evaluate how the EBV infection modulates B and T-cell subsets in SjS, including as controls Rheumatoid arthritis patients (RA) and healthy participants (HC).SjS patients
doi:10.21203/rs.3.rs-109255/v1
fatcat:ej37ibunu5do7hhgk5km46djji